Blastic crisis and myelofibrosis, simultaneous complications in a case of chronic myelocytic leukemia.
نویسنده
چکیده
A case of chronic myelocytic leukemia is reported. He developed blastic crisis as well as myelofibrosis, simultaneously as a complication, after 1-1/2 years treatment with myeleran.
منابع مشابه
Peripheral Leukocyte Kinetic Studies of Acute Leukemia in Relapse and Remission and Chronic Myelocytic Leukemia in Blastic Crisis
I T HAS BEEN ONLY RECENTLY that significant progress has been made in the study of leukocyte kinetics and cell proliferation in acute leukemia. This became possible with the introduction of tritiated thymidine (H3TdR), a labeled precursor specffic for DNA.’ With the technic of radioautography, this labeled compound has been employed in vivo to investigate the leukemic cell cycle and cell prolif...
متن کاملTrisomy 13 in a case of myelofibrosis with myeloid metaplasia with early blastic transformation.
We describe a case of early myeloid blastic transformation in a 64-year-old man suffering from myelofibrosis with myeloid metaplasia. Both chronic and blastic phase cytogenetic analysis showed trisomy 13 to be the sole chromosome aberration. A potential role for this rare abnormality in determining such an unusually poor clinical outcome is discussed.
متن کاملPeripheral Leukocyte Kinetic Studies of Acute Leukemia in Relapse and Remission and Chronic Myelocytic Leukemia in Blastic Crisis
I T HAS BEEN ONLY RECENTLY that significant progress has been made in the study of leukocyte kinetics and cell proliferation in acute leukemia. This became possible with the introduction of tritiated thymidine (H3TdR), a labeled precursor specffic for DNA.’ With the technic of radioautography, this labeled compound has been employed in vivo to investigate the leukemic cell cycle and cell prolif...
متن کاملPeripheral leukocyte kinetic studies of acute leukemia in relapse and remission and chronic myelocytic leukemia in blastic crisis.
I T HAS BEEN ONLY RECENTLY that significant progress has been made in the study of leukocyte kinetics and cell proliferation in acute leukemia. This became possible with the introduction of tritiated thymidine (H3TdR), a labeled precursor specffic for DNA.’ With the technic of radioautography, this labeled compound has been employed in vivo to investigate the leukemic cell cycle and cell prolif...
متن کاملPersistence of chronic myelocytic leukemia despite deletion of rearranged bcr/c-abl sequences in blast crisis
We report on a Ph+ chronic myelocytic leukemia (CML) case, cytogenetically characterized by the occurrence of a second Philadelphia (Ph) chromosome in lymphoid blast crisis of T cell lineage. In situ hybridization analyses showed a deletion of translocated c-abl sequences, present on the Ph during chronic state, from both Ph in acute state. Moreover, Southern blot analyses of blastic cells exhi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- JPMA. The Journal of the Pakistan Medical Association
دوره 31 7 شماره
صفحات -
تاریخ انتشار 1981